Brit J Hosp Med
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Blood transfusion-related immunomodulation results in either immune activation, associated with a variety of transfusion reactions, or immunosuppression, associated with an increased predisposition to infections and post-surgical cancer recurrence. This article reviews the major complications associated with blood transfusion.
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Allogeneic blood transfusions are associated with risks and unfavourable outcomes. Blood conservation provides an alternative, with potential to improve patient care with limited or no blood transfusion. Many approaches are available, but the most essential ones are simple and cost free.