Chinese Med J Peking
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Chinese Med J Peking · Dec 1998
Single-strand conformation polymorphism for analysis of genomic variability of hepatitis C virus nonstructure 5A region.
To establish a convenient method to detect the genomic population with hepatitis C virus (HCV) at nonstructure 5A (NS5A) region and to determine the correlation between the genomic population complexity at NS5A region and disease stage. ⋯ These results suggest that the genomic variability of HCV at NS5A region increases with the progression of liver disease, and this may be closely related to the clinical features of type C liver disease.