Chinese Med J Peking
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Chinese Med J Peking · Aug 1998
Contribution of the absence of aspartic acid at position 57 of the HLA-DQ beta chain to predisposition to insulin-dependent diabetes mellitus in a southern Chinese population.
To investigate the association of the absence or presence of aspartic acid at position 57 of the HLA-DQ beta chain (NA or A) with susceptibility or resistance to insulin-dependent diabetes mellitus (IDDM) in a Southern Chinese population. ⋯ The present study suggests that the NA confers the susceptibility to IDDM, while the A confers the protection against IDDM in patients of Southern Chinese origin. These associations are more clearcut in childhood-onset IDDM patients.
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Chinese Med J Peking · Aug 1998
Sma I, Hha I, Msp I and Rsa I restriction fragment length polymorphisms in the von Willebrand factor gene of Chinese population.
To study Sma I, Hha I, Msp I and Rsa I restriction fragment length polymorphisms in vWF gene of Chinese population. ⋯ The allele frequencies and theoretical rates of these polymorphisms in vWF gene are different between Chinese populations and Caucasians. They should be useful for the carrier detection and prenatal diagnosis in vWD families of Chinese.