Chinese Med J Peking
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Chinese Med J Peking · Aug 2001
Randomized Controlled Trial Clinical TrialEffects of extrinsic positive end-expiratory pressure on work of breathing in patients with chronic obstructive pulmonary disease.
To investigate the effects of extrinsic positive end-expiratory pressure (PEEPe) on work of breathing in patients with chronic obstructive pulmonary disease (COPD) and their corresponding mechanism. ⋯ WOBp decreases gradually as PEEPe is increased. WOBp decreases by narrowing the difference between the alveolus pressure and the central airway pressure at the end of expiration when PEEPe is applied.