Chinese Med J Peking

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• Chinese Med J Peking · Jan 2003

  Randomized Controlled Trial Multicenter Study Clinical Trial

  A double-blind, randomized, placebo-controlled multicenter study of oseltamivir phosphate for treatment of influenza infection in China.

  To evaluate the efficacy and safety of oseltamivir phosphate as treatment for naturally acquired influenza infection. ⋯ Oseltamivir was effective and well tolerated as treatment of early naturally acquired influenza.

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• Chinese Med J Peking · Jan 2003

  Sequential non-invasive mechanical ventilation following short-term invasive mechanical ventilation in COPD induced hypercapnic respiratory failure.

  To estimate the feasibility and the efficacy of early extubation and sequential non-invasive mechanical ventilation (MV) in chronic obstructive pulmonary disease (COPD) with exacerbated hypercapnic respiratory failure. ⋯ In COPD patients requiring intubation and MV for pulmonary infection and hypercapnic respiratory failure, early extubation followed by non-invasive MV initiated at the point of PIC window significantly decreases the invasive and total durations of ventilatory support, the risk of VAP, and the duration of ICU stay.

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