Chinese Med J Peking
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Chinese Med J Peking · Jul 2010
Randomized Controlled TrialA small-dose naloxone infusion alleviates nausea and sedation without impacting analgesia via intravenous tramadol.
Early studies showed that naloxone infusion decreases the incidence of morphine-related side effects from intravenous patient-controlled analgesia. This study aimed to determine whether naloxone preserved analgesia while minimizing side effects caused by intravenous tramadol administration. ⋯ A small-dose naloxone infusion could reduce tramadol induced side effects without reversing its analgesic effects.