Chinese Med J Peking
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Chinese Med J Peking · Jan 2016
Elimination Rate of Serum Lactate is Correlated with Amyotrophic Lateral Sclerosis Progression.
Mitochondrial dysfunction plays an important role in the pathogenesis of amyotrophic lateral sclerosis (ALS). We aimed to demonstrate mitochondrial dysfunction in ALS using a lactate stress test and to examine the relationship between mitochondrial dysfunction with motor deterioration. ⋯ There is a potential linear relationship between ER and motor deterioration in ALS. Slower ER might be associated with faster disease progression.