Chinese Med J Peking
-
Chinese Med J Peking · Mar 2016
ReviewApplication and Exploration of Big Data Mining in Clinical Medicine.
To review theories and technologies of big data mining and their application in clinical medicine. ⋯ Big data mining has the potential to play an important role in clinical medicine.
-
Chinese Med J Peking · Feb 2016
Changes in the Bispectral Index in Response to Loss of Consciousness and No Somatic Movement to Nociceptive Stimuli in Elderly Patients.
Bispectral index (BIS) is considered very useful to guide anesthesia care in elderly patients, but its use is controversial for the evaluation of the adequacy of analgesia. This study compared the BIS changes in response to loss of consciousness (LOC) and loss of somatic response (LOS) to nociceptive stimuli between elderly and young patients receiving intravenous target-controlled infusion (TCI) of propofol and remifentanil. ⋯ In elderly patients, BIS can be used as an indicator for hypnotic-analgesic balance and be helpful to guide the optimal administration of propofol and remifentanil individually.
-
Chinese Med J Peking · Jan 2016
Elimination Rate of Serum Lactate is Correlated with Amyotrophic Lateral Sclerosis Progression.
Mitochondrial dysfunction plays an important role in the pathogenesis of amyotrophic lateral sclerosis (ALS). We aimed to demonstrate mitochondrial dysfunction in ALS using a lactate stress test and to examine the relationship between mitochondrial dysfunction with motor deterioration. ⋯ There is a potential linear relationship between ER and motor deterioration in ALS. Slower ER might be associated with faster disease progression.