Dtsch Arztebl Int
The most recent articles from:
Dtsch Arztebl Int
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Because of the increased risk of acute renal failure (ARF), the use of cyclooxygenase (COX) inhibitors is not recommended in patients with decompensated hepatic cirrhosis. Metamizole is not a classic COX inhibitor, but there are insufficient data to support its safe use. In this study, we investigate the effect of metamizole on the risk of ARF in these patients. ⋯ Metamizole therapy, especially at high doses, should only be used with a high level of caution in patients with decompensated cirrhosis.