Dtsch Arztebl Int
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Comment Letter
Correspondence (letter to the editor): Remember self-help.
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Comment Letter
Correspondence (letter to the editor): Research is needed.
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The recommendations in clinical guidelines are based on clinical trial findings and expert opinion. The influence of drug companies on these two factors is illustrated with two examples. ⋯ Public access to all trial data must be ensured so that independent evaluations are possible. We take the view that the responsibility for creating guidelines should be borne by authors and organizations that do not have any conflicts of interest.
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A case report is a narrative that describes, for medical, scientific, or educational purposes, a medical problem experienced by one or more patients. Case reports written without guidance from reporting standards are insufficiently rigorous to guide clinical practice or to inform clinical study design. Our primary objective was to develop, disseminate, and implement systematic reporting guidelines for case reports. ⋯ We believe the implementation of the CARE (CAse REporting) guidelines by medical journals will improve the completeness and transparency of published case reports and that the systematic aggregation of information from case reports will inform clinical study design, provide early signals of effectiveness and harms, and improve healthcare delivery.