Gac Med Mex
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COVID-19, caused by the betacoronavirus SARS-CoV-2, has overwhelmed the world's health systems. ⋯ In this study, the epidemiological characteristics and main comorbidities in Mexican patients with SARS-CoV-2 infection were identified.
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Observational Study
Placental pathology and perinatal risk during the COVID-19 pandemic.
Respiratory and immune changes during pregnancy can lead to viral infections. In coronavirus disease 2019 (COVID-19), clinical characteristics and perinatal risks are difficult to assess and are relatively unknown. ⋯ COVID-19 asymptomatic infection potentiates preexisting prothrombotic profile, thus increasing the risk of placental thrombosis and, potentially, of thrombosis in pregnant women.
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In December 2019, a new coronavirus emerged in Wuhan, China, which has become a global health problem. ⋯ Restrictive measures and social distancing, as well as promptness of their implementation, are necessary for achieving a decrease in COVID-19 infections and mortality.
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Sarcoplasmic reticulum Ca2+ ATPases (SERCA) enzymes are essential for intracellular Ca2+ homeostasis. SERCA genes (ATP2A1-3) encode for different functional isoforms of the protein, whose expression or function is altered in several types of cancer, such as gastric and oral, as well as colon, breast, lung, thyroid, liver, and prostate cancer, among others. However, the role played by SERCA pumps in carcinogenesis is unknown. ⋯ SERCA expression might function as a tool to differentiate breast cancer subtypes, which have different treatment requirements.