Gac Med Mex
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Sepsis continues to be a major cause of morbidity and mortality. Evidence is emerging from observational studies and basic science research that statins might be associated with reduced mortality in sepsis. Statins have diverse immunomodulatory and antiinflammatory properties independent of their lipid-lowering ability. ⋯ It suggests an urgent need to investigate the pharmacology of these drugs and reappraise their therapeutic indications in critically ill patients. If this finding is supported by prospective controlled trials, statins may play an important role in sepsis related mortality. By the other hand statins are significantly cheaper than other therapies that have been shown to improve outcome in sepsis, and the demonstration of mortality benefit would have enormous cost-benefit implication.
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Review Comparative Study
[Pulmonary complications of hepatic cirrhosis: portopulmonary hypertension and hepatopulmonary syndrome. The paradox of pulmonary vasoconstriction and vasodilation].
Cardiopulmonar complications in chronic liver diseases were described 100 years ago. Altough both hepatopulmonary sindrome and portopulmonary hypertension originates from liver damage, clinical findings and diagnosis are very different. ⋯ In this review we analyze the most important issues on hepatopulmonary sindrome and portopulmonary hypertension. These complications,under the cornerstone of portal hypertension are characterized by pulmonary constriction and dilatation, respectively.
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Historical Article
[First case report in Mexico of a diaphragmatic hernia, by Agustín Arellano in 1839].
Reports on partial lacking of the diaphragm and diaphragmatic hernia date to seventeenth century reports. In 1939 Arellano published in Mexico, a necropsy case of diaphragmatic hernia with holoprosencephaly and cyclocephaly. Agustín Arellano's was the the fifth or sixth report ever published worldwide and his manuscript was reported nine years before Bochdalek's publication. ⋯ It is well known that, at the time, the quality ofscientific publications of this Mexican medical researcher could be compared to the level of any medical publication in the developed world. It is worth noting that the Journal were Arellano's work was published, named "Periodico de la Academia de Médicina de Mégico (sic), "founded and directed by Dr. Manuel Carpio in 1836, is the direct precursor of the present-day "Gaceta Médica de México" the oldest current medical journal in the Americas.
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Controversies regarding the surgical management of chronic subdural hematoma still remain. The objective of the present study was to describe our experience with twist-drill craniostomy. ⋯ Twist-drill craniostomy is a less time consuming, safe, effective, and cost-efficient method for the treatment of chronic subdural hematoma.
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Randomized Controlled Trial
[Effectiveness of supervised aerobic exercise in alternating weekdays associated with glycosylated hemoglobin levels among type 2 sedentary diabetic patients].
[corrected] Determine the extent to which levels of glycosylated hemoglobin levels among type 2 sedentary diabetic patients change when performing aerobic exercises two or three times a week. ⋯ Moderate aerobic exercise was well tolerated showing a significant decrease on HbA1c even among the 2 day group.