Gac Med Mex
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Home confinement policies during the COVID-19 pandemic limited sun exposure and may have influenced on vitamin D levels. ⋯ The restrictions due to the COVID-19 pandemic led to a higher frequency of hypovitaminosis D and lower frequency of optimal values.
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One of the population groups at higher risk of suicide is that of people who attend mental health institutions. ⋯ The findings highlight the importance of early identification of risk factors that may contribute to an increase in suicidal behaviors.
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The impact of diabetes mellitus has been shown to be differentially expressed between social groups. ⋯ The inequalities present in diabetes mortality should be considered for the design of health strategies.
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Stereotactic body radiation therapy (SBRT) is a modality that delivers high doses of radiation to a well-defined tumor target in a single or a few fractions and with high precision, which significantly reduces the dose received by surrounding normal tissues. SBRT is indicated for inoperable, early stage (T1 and T2) primary non-small cell lung cancer, lung metastases with a controlled primary tumor, prostate tumors and oligometastatic disease. Despite the lack of long-term or phase III studies, efficacy results in local control are higher than 90%, with similar toxicity to that reported with conventional fractionated radiotherapy. This article describes SBRT technology and technique, along with clinical applications, indications and limitations of this therapeutic modality.
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Treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals achieves a sustained virologic response rate higher than 95%. However, virologic failure remains a clinical challenge, and data on retreatment are limited, especially in special populations such as liver transplant (LT) recipients. ⋯ In our series, sofosbuvir plus GLE/PIB for 12 weeks is an effective and safe salvage therapy after LT in patients previously treated with NS5A inhibitors.