Gac Med Mex
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Epigenetic and genomic imprinting alterations of the 11p15.5 region cause excessive or deficient growth, which result in Beckwith-Wiedemann syndrome (BWS) or Silver-Russell syndrome (SRS), respectively. ⋯ Adequate genotype-phenotype correlation was observed with the methylation defects that were identified, which confirms the usefulness of MLPA as a first-line study in patients diagnosed with BWS and SRS.
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There are aspects of COVID-19 pathogenesis that are still unknown. ⋯ SARS-CoV-2 VL determined at hospital admission might classify risk simultaneously with other factors described in COVID-19.
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To determine weight, height and body mass index (BMI) of schoolchildren from the La Mancha-Centro health area and compare them with those determined by the Spanish Cross-sectional Growth Study 2010 (SCGS-2010). ⋯ Anthropometric parameters of schoolchildren from La Mancha-Centro do not significantly differ from national standards; however, preadolescent males from La Mancha-Centro weigh almost 4 kg more.
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In Mexico, the prevalence of childhood obesity is 35%, and it continues to increase. ⋯ Current self-image and body satisfaction are different with and without obesity. The relationship between self-esteem and depressive symptoms begins at school age.
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COVID-19 superspreader events have occurred when symptomatic individuals without wearing face masks boarded buses. ⋯ Strict nonpharmacological preventive interventions substantially reduced the risk of COVID-19 super-spreader events in buses boarded by presymptomatic individuals.