Hippokratia
-
The non-communicating rudimentary horn of a unicornuate uterus is the rare result of abnormal development of the Müllerian ducts during embryogenesis. Case description: We report a rare condition of a pregnancy of eight weeks of gestation in a non-communicating rudimentary horn of a unicornuate uterus, which was diagnosed without specific symptoms and treated through laparoscopy. ⋯ Early diagnosis and treatment are essential to prevent the high maternal risk of life-threatening bleeding complications. HIPPOKRATIA 2019, 23(2): 92-94.
-
Atherosclerosis of the large arteries of the neck could be related to the cognitive and motor deficit. We investigated if the atherosclerosis of common carotid and femoral arteries in patients with multiple sclerosis (MS) is directly linked with a disability and has an inverse relationship with cognitive performance. ⋯ Our results suggest that the degree of atherosclerosis, as calculated by the ATHUS score, is directly related to low cognitive score and higher sensory and motor disability. HIPPOKRATIA 2019, 23(2): 81-86.
-
Autophagy is an inducible intracellular process that has been studied mostly in cancer and less in inflammatory diseases. To establish the relation between cholecystitis (calculous and acalculous) and autophagy, we studied the expressions of immunohistochemical markers Beclin-1, LC3A, and Ki-67 in gallbladder epithelium and their significance in the induction of autophagy. ⋯ In the epithelium of calculous cholecystitis, overexpression of LC3A is related to Beclin-1 overexpression, which reinforces the view that Beclin-1 promotes autophagy in stone cholecystitis. HIPPOKRATIA 2019, 23(2): 64-69.
-
Intramedullary nailing is the "gold standard" treatment modality of diaphyseal fractures of the tibia. However, when the same method is used for extra-articular fractures of the proximal tibia, various problems may occur, like malalignment, loss of reduction, and non-union. The objective of the present biomechanical study was to compare the stability of six tibial nails when these are used for the treatment of unstable, extra-articular, proximal tibial fractures. ⋯ Solid nails provide more rigidity compared to cannulated ones, and the maximum number of proximal screws in all possible directions should be used in order to achieve maximum stability. HIPPOKRATIA 2019, 23(2): 58-63.