Natl Med J India
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A 15-year-old girl developed symptoms suggestive of malignant hyperthermia during a laparoscopic appendicectomy for acute appendicitis. The triad of masseter spasm, hypercarbia and hyperthermia within 30 minutes of exposure to triggering factors was present and was treated successfully with dantrolene. ⋯ The problems faced in the post-acute phase included the development of thrombophlebitis due to dantrolene use in our patient, as well as paucity of testing centres for malignant hyperthermia both locally and in the region. This prevented us from making a definitive diagnosis in our patient.
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India is poised to introduce rotavirus vaccines into its routine childhood immunization programme. Substantial data ara available on disease and economic burden of rotavirus gastroenteritis and on circulating strains in India, which highlight the public health need for a rotavirus vaccine. ⋯ The Government of India has announced that the vaccine will be included in the universal immunization n programme. Careful planning and preparation for post-licensure impact and safety evaluations will ensure that additional high quality benefit-risk data will be available for India.