Niger J Clin Pract
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The role of monocytes and high-density lipoprotein (HDL) levels in the pathophysiology of cardiovascular disease (CVD) is well known. However, the relationship between monocytes to HDL-cholesterol ratio (MHR) and CVD in chronic obstructive pulmonary disease (COPD) patients has not been investigated previously. We, therefore, aimed to investigate the predictor role of MHR in the development of CVD in subjects with COPD. ⋯ MHR is significantly associated with CVD in COPD patients. Further prospective studies are warranted to elucidate the predictive value of MHR in COPD patients.
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There were no comparing data about the effect of recently developed file system OneCurve on apical debris extrusion. ⋯ Under the conditions of this in vitro study, ProTaper-Next, 2Shape, and OneCurve files had similar apical debris extrusion values. Cervical preflaring of root canals did not affect the amount of apically extruded debris.
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Review Meta Analysis
Immunosuppressive agents in the treatment of IgA nephropathy: A meta-analysis of clinical randomized controlled literature.
IgA nephropathy (IgAN) is the most common form of glomerulonephritis in the world. Immunosuppressive therapy has been widely used in IgAN patients at home and abroad. The present meta-analysis aimed to assess the efficacy and safety of different immunosuppressive agents in patients with biopsy proven IgAN, in order to provide guidance for the clinical treatment of IgAN treatment options. ⋯ Compared with CTX, MMF showed higher effectiveness (CR/PR; RR, 3.32; 95% CI, 1.83-6.01; P< 0.0001) and LEF showed higher effectiveness (CR/PR; RR, 1.85; 95% CI, 1.17C-2.92; P = 0.009) with a lower incidence of adverse events. The results showed that immunosuppressive agents are a promising strategy and should be investigated further. MMF is the safest, the best therapeutic result and the least side effects than the other immunosuppressive agents.
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To study the prevalence of middle mesial and middle distal canals in permanent mandibular molars in Egyptian subpopulation using micro-computed tomography. ⋯ A higher percentage of MM canal was detected followed by the MD canal. The least significant was both canals occurring within the same molar. The percentage of the confluent configuration was the highest. The apt knowledge of the variations of the root canal system anatomy and the respect of the discrepancies associated with diverse demographic areas will ensure the proper management of each tooth with endodontic involvement and its long-term success.
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Handedness is one of the individual characteristics that causes different mental and practical capabilities including different abilities to perform oral hygiene instructions. It seems that the right-handed and left-handed individuals have different ability in brushing and removing plaque at different areas of the mouth. ⋯ A relationship cannot be considered between the handedness of children and their oral health status.