Niger J Clin Pract
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Numerous studies have reported a relationship between human immune deficiency virus (HIV)/acquired immune deficiency virus (AIDS) and auditory functions. There is a dearth of information on the prevalence of hearing loss among newly diagnosed HAART naïve adult patients. Aim: This study therefore provides baseline information on the prevalence of hearing loss among newly diagnosed HAART naïve adult patients in Port Harcourt and serves as a reference for the role of HAART in HIV related hearing loss and for future studies. ⋯ There was significant proportion of hearing loss among newly diagnosed HAART naive adult patients in Port Harcourt.
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The effects of commonly used antimicrobial and anticariogenic agents on the adhesion of pit and fissure sealants were investigated in this study. ⋯ Er, Cr: YSGG laser and CPP-ACP containing paste are alternative methods for pre-application of fissure sealants.
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Observational Study
Determination and comparison of potential drug-drug interactions using three different databases in northern cyprus community pharmacies.
Drug interactions are common drug-related problems that can lead to adverse drug reactions and hospitalization. ⋯ This study showed that Medscape detected more potential DDIs than Drugs.com and Lexicomp. Therefore, we propose that more than one database should be used to evaluate and identify pDDIs in pharmacy.
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The relationship between blood pressure (BP) trajectories and outcomes in patients with peripartum cardiomyopathy (PPCM) is not clear. Aim: The study aimed to assess the clinical features and outcomes (all-cause mortality and unrecovered left ventricular [LV] systolic function) of PPCM patients grouped according to their baseline systolic BP (SBP). ⋯ In our cohort of PPCM patients, one-fifth was hypotensive at presentation. SBP <90 mmHg at presentation was associated with a four-fold higher risk of all-cause mortality during a median follow-up of 18 months.
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Randomized Controlled Trial
Does smoking affect the onset time of sensory blocks or the duration of motor blocks in parturient women? A randomized controlled trial.
In general, smoking or exposure to secondhand smoke is still common worldwide, and the rate of smoking in women of childbearing age is gradually increasing. Cesarean section rates have been increasing in recent years, and anesthesia guidelines recommend regional anesthesia for cesarean sections. Since nicotine and local anesthetics have different effects on ligand-gated ion channels, smoking may affect spinal anesthesia in pregnant women. Aim: The aim of this study was to investigate the effects of smoking on spinal anesthesia, which is applied for cesarean sections in pregnant women. Patients and. ⋯ In conclusion, the pregnant women who smoked had longer motor block onset times, shorter motor block durations, higher VAS scores, and lower patient satisfaction levels.