Niger J Clin Pract
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Schistosomiasis is a neglected infectious tropical disease that is second in occurrence only to hookworm infection in sub-Saharan Africa. Presently, chemotherapy is the main method of control and treatment of this disease due to the absence of a vaccine. ⋯ A number of plant-derived compounds, including alkaloids, terpenes and phenolics, have displayed in vitro and in vivo efficacy against Schistosoma species. This review explores how the application of nanotechnology can improve the efficacy of these plant-derived schistosomicidal compounds through the use of nano-enabled drug delivery systems to improve bioavailability.
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The genital system remains one of the most common sites of carcinogenesis in women. Advances in surgery, radiation treatment, and chemotherapy have increased their efficacy and many patients survive for many years after their initial diagnosis. The eye is a rare site of metastasis from gynecological cancer due to its distant location from the genitalia. ⋯ The mean disease-free interval was found at 25.7 months and mean survival time after the eye metastasis was 13.5 months. Refractory disease was identified as the most important risk factor associated with mortality. Because eye metastasis has such a dismal prognosis, all gynecologists who treat oncological patients should be highly suspicious for reported eye complaints.
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Shoulder dystocia is an emergency and risky situation that most likely directly involves midwives. ⋯ Using a high fidelity simulation model in training increased midwives' shoulder dystocia management skills and knowledge.
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The whole root canal disinfection is crucial in terms of long-term endodontic success. In this context, applying medicaments following effective irrigation activation procedures becomes an important point. ⋯ Medicament penetration depends on the type of medicament, activation procedures, and root canal level. The TAP may be preferred following the ultrasonic activation in terms of long term root canal treatment success.
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Review Case Reports
A case of diffuse alveolar hemorrhage after orthognathic surgery: Case report with the literature review'.
Diffuse alveolar hemorrhage (DAH) disease is a rare but acutely developing condition that may occur after general anesthesia, if not diagnosed and treated on time, could be life-threatening. Orthognathic surgeries, frequently performed for functional and esthetic correction, are generally composed of a young population in their twenties with no other disease. The aim of presenting this case report was to describe the etiology, diagnosis, and treatment of DAH to emphasize the importance of timely diagnosis.