Niger J Clin Pract
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Although, sickle cell trait (SCT) was considered a benign condition with most patients being asymptomatic, however, there is an impressive increase in the number of sudden deaths in the military recruits and athletes, which has led to SCT as a rapidly emerging medical issue. Genetic factors have been extensively investigated in the etiopathogenesis of SCT but, environmental factors have not been studied in depth. ⋯ This study's findings appear to suggest that hyperthermia could be excluded as one of the major factors inducing sickling complications during exhausting exercise. Long-term studies in the future are recommended in this area, particularly to assess the effect of high temperature and sudden death in SCT.
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Depression is a widespread disorder with either an independent or interrelated relationship with chronic disease. ⋯ Depression is quite prevalent in patients with SCD though it is still being overlooked. Several clinical and laboratory indices found to be closely linked to depression. Constellations of these factors may help early recognition of depression and disease severity modulation.
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Gestational trophoblastic disease (GTD) is a rare and often curable group of diseases that has a large range of morphological features, sometimes making the diagnosis difficult. ⋯ In the Al Madinah region of KSA, the most common type of GTD in women was HM. Most GTD cases were found in women between the ages of 31 to 40 years. The frequency of GTD, its histopathological subtypes are consistent with most of the studies on GTD; however, larger studies involving multiple centers are recommended, for confirmation of present study's findings.
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Ureteropelvic junction obstructions (UPJOs) occur more frequently on the left than on the right side. Among patients diagnosed during the neonatal period, those with left-side UPJO have a more severe course than those with right-side UPJO. ⋯ Those with left-side UPJO had a more severe course than those with right-side UPJO.
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Diarrhoea is a major cause of childhood morbidity and mortality in developing countries including Nigeria. Rotavirus is a leading cause of acute watery diarrhoea in children under 5 years of age. ⋯ This study has confirmed that rotavirus is an important cause of childhood diarrhoea. The burden of childhood diarrhoea can be reduced by introduction of vaccines, and children of 1 year old and younger will benefit from this vaccine as most study participants have not been vaccinated. Creating awareness on prevention and control of this infection with mass vaccination will go a long way in reducing the prevalence and mortality rate of rotavirus diarrhoea.