Niger J Clin Pract
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Comparative Study
Treatment Outcome of Macular Hole Associated with Rhegmatogenous Retinal Detachment.
Macular holes are an infrequent association with rhegmatogenous retinal detachment, increasing the complexity of surgery and affecting outcome. ⋯ Single-surgery retinal reattachment rate and macular hole closure using any of the techniques is high, and none showed superiority.
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The mentioned advantages of bulk-fill composite resin and high-viscosity glass ionomer restorative materials have increased their use in restorative dentistry in recent years; accordingly, the bonding of these materials to dental tissues and their mechanical properties have become more important. ⋯ It can be concluded that preheating before application may increase the shear bond strength of reinforced high-viscosity glass ionomer.
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Observational Study
Effects of Maternal Dyslipidemia on Maternal and Perinatal Outcomes in Enugu, Southeast Nigeria: A Prospective Cohort Study.
Maternal dyslipidemia is one of the consistent metabolic changes during pregnancy. There is a controversy as to whether maternal lipid disturbances in early pregnancy are associated with adverse maternal and perinatal outcome. ⋯ Maternal dyslipidemia is associated with some adverse perinatal outcomes such as LBW, IUFD, still birth, and birth asphyxia. These findings would guide in the care of pregnant women with dyslipidemia.
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Nowadays, the increasing importance of mother-infant contact, the significant impact of mother and baby's sleep quality, and the positive effects on breastfeeding are factors that make breastfeeding sleep important. ⋯ The literature is very limited in assessing the effects of breastsleeping on mothers' sleep quality and attachment. This study found that breastsleeping did not affect maternal sleep quality and attachment.
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Colorectal carcinoma (CRC) is the most common gastrointestinal malignancy in Nigeria with a dismal 5-year survival rate. Interactions between the CD8+ T-lymphocytes and the immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-ligand 1 (PD-L1) expressions are important. Novel antibodies have been developed against these immune checkpoints and have been found to improve clinical outcome in many solid organ malignancies. ⋯ PD-L1 expression in CRC was low (5.6%) and showed strong associations with higher tumor grades (P < 0.013), right-sided tumors (P < 0.002), and rectal cancer. There was no association with age, tumor stage, and lymph node status.