Niger J Clin Pract
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Controlled Clinical Trial Observational Study
Effect of terlipressin infusion therapy on recipient's hepatic and renal functions in living donor liver transplantations: Experience from a tertiary hospital.
Patients with end-stage liver disease are prone to hemodynamic disturbances which may be aggravated with liver transplantation. Blood pooling in splanchnic area and portal hypertension cause reduction in central blood volume. Terlipressin reduces mesenteric and hepatic blood flow, causing vasoconstriction in the smooth muscles of the arteries in the splanchnic region. ⋯ This may be a result of randomization defect of our retrospective study design. Many prospective randomized studies should be planned to reach more accurate results.
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Cutaneous changes commonly occur in chronic kidney disease (CKD), however, there is limited information on its effect on quality of life of these patients. This study determined the prevalence and pattern of skin changes in CKD patients and their effects on the dermatology life quality index (DLQI) of the patients. ⋯ Skin changes occur commonly in CKD patients and significantly affected their DLQI. This study highlights the significant burden that skin changes add to CKD.
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Dental office is an ideal screening place to identify undiagnosed/uncontrolled patients with hypertension. The aim of this study was to assess the knowledge and behavior of dentists toward performing proper management of hypertensive patients in Saudi Arabia. ⋯ There is a lack of knowledge and behavior toward proper management of patients with hypertension in our dental sociality. Broadening the breath of dentists' responsibilities to include screening and working together with physicians will help improve the community dental and general health of visiting patients and should be the goal of all dentists.
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Chronic kidney disease (CKD) prevalence is rising in Nigeria. Most cases are diagnosed as end stage disease despite availability of formulae to estimate glomerular filtration rate (GFR). Existing formulae, none of which is modelled on Nigerian variables, give different estimates. This study tests the significance of the difference in the estimates obtained using Modified Diet in Renal Disease (MDRD) Study and Chronic Kidney Disease-Epidemiology (CKD-Epi) formulae. ⋯ MDRD significantly underestimated GFR compared to CKD-Epi in a Nigerian population. This bias was proportional and increased as mean eGFR increased. MDRD and CKD-Epi models do not agree in their measurements of eGFR and should not be used interchangeably. There is urgent need for further studies to develop GFR estimating model on Nigerian variables.
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Alteration in the homeostasis of trace elements such as magnesium may play a role in the development of epileptic seizures. This study aims to investigate the levels of serum magnesium in people with idiopathic generalized epileptic (IGE) seizures and symptomatic seizures in Northeast Nigeria. ⋯ This study suggests that low serum magnesium and calcium may play a role in IGE, and supplementation may be useful in reducing seizures in Black patients with epilepsy.