Niger J Clin Pract
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Community-acquired infection caused by extended-spectrum beta-lactamase (ESBL)-producing microorganisms has an increasing frequency. ⋯ The relative high prevalence of fecal carriage of ESBL-producing bacteria in community warrants further study in this field including developing policies about antimicrobial use and close monitoring of resistance patterns.
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Eyelash extensions involve the attachment of synthetic eyelashes made of chemical fibers or other materials onto natural eyelashes. It has become common practice among Nigerian women for various reasons. Aim/Objectives: The aim is to assess eyelash extension use among students of a higher institution in Nigeria, the reasons for its use and related eye complications. ⋯ Eyelash extension use is popular among young female students of higher institutions commonly for esthetic reasons (often because they desire to become more beautiful). Majority of them experience one ocular symptom or the other. Attention should, therefore, be paid to the potential health risk of the procedure and its use should be made much safer for our women.
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Pancreatic carcinoma is the most lethal cancer, with a 5-year survival rate of <5%. Hyperglycemia is one of the severe adverse drug reactions (ADRs) in cancer treatment. The aim was to analyze the blood glucose-related ADR of antineoplastics in treating pancreatic cancer. ⋯ Pancreatic carcinoma is an aggressive malignancy typically associated with severe hyperglycemia. Furthermore, hyperglycemia is one of the severe ADRs from antineoplastics, which must be paid special attention to when treating in pancreatic carcinoma, especially doxorubicin, fluorouracil, and gemcitabine. Such real-time monitoring or pretreatment gene test can be suggested.
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Comparative Study
Microarray analysis of the gene expression profile in triethylene glycol dimethacrylate-treated human dental pulp cells.
Triethylene glycol dimethacrylate (TEGDMA) is an important resin monomer commonly used in the structure of dental restorative materials. Recent studies have shown that unpolymerized resin monomers may be released into the oral environment and cause harmful biological effects. We investigated changes in the gene expression profiles of TEGDMA-treated human dental pulp cells (hDPCs) following short- (1-day) and long-term (7-days) exposure. ⋯ Our results suggest that TEGDMA can change the many functions of hDPCs through large changes in gene expression levels and complex interactions with different signaling pathways.
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Case Reports
Type A intramural hematoma in a patient with acute coronary syndrome mimicking acute Type A aortic dissection.
Intramural hematoma (IMH) of ascending aorta is a rare but potentially lethal form of acute aortic syndrome (AAS). It is characterized by a hematoma within the media layer of the aorta secondary to rupture of the vasa vasorum in the absence of an intimal tear. However, the theory of "micro-tear" which cannot be easily detected has been raised. ⋯ The CAG was terminated with a suspicion of Type A AD. The diagnosis of IMH starting just above RCA ostium with a thickness of 18 mm was made with computed tomographic angiography. An emergent surgical repair of the aorta and one-vessel coronary artery bypass graft surgery was performed successfully in our patient.