Niger J Clin Pract
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Pregnancy may exacerbate the frequency and severity of some dental problems. However, most pregnant women avoid going to the dentist. ⋯ In the present study, it is seen that pregnant women do not have adequate oral hygiene. The reasons were listed as various false beliefs and lack of sufficient knowledge. Health professionals should provide information about oral hygiene to pregnant women and direct them to the dentist.
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Prolonged perinatal asphyxia (PA) may cause hypoxic-ischemic damage to the brain. The aim of this study was to investigate the brain diffusion changes of patients with PA and examine the relationship with brain damage. ⋯ In neonates with severe perinatal asphyxia, brain damage can be evaluated on diffusion-weighted imaging (DWI) of the cerebral deep white matter and basal ganglia. DWI, imaging with conventional brain MRI comes to the fore in clinical importance in PA patients.
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The COVID-19 pandemic caused by SARS-CoV-2 is an unparalleled health risk, needing fast antiviral medication development. One of the most effective strategies for developing therapies against novel and emerging viruses is drug repurposing. Recently, systems biology approaches toward the discovery of repurposing medications are gaining prominence. ⋯ Interestingly, some of the proposed drugs have demonstrated inhibitory effects against SARS-CoV-2, as supported by literature evidence. Overall, the drug repurposing method described here will help develop potential antiviral medications to treat emerging COVID strains.
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Review
Granulomatosis with Polyangiitis: A Rare but Clinically Important Disease for the Otolaryngologist.
Granulomatosis with polyangiitis (GPA) is rare but debilitating autoimmune disease and commonly presents with sinonasal as well as other head and neck symptoms. ⋯ This review illustrates the important role that an otolaryngologist can play in the work up and symptom management of patients with GPA. Knowledge of the common presenting symptoms as well as more rare presentations of GPA is extremely important for otolaryngologists as prompt diagnosis and management is extremely important to avoid significant morbidity and mortality.
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Breast cancer is the most prevalent cancer type globally. The female breasts are important for beauty and sexuality, comprising the body image, which includes the individual self-perception and others. This varied perception may influence the quality of life of individuals with breast cancer. ⋯ Negative body image results in poorer QoL in breast cancer patients, and this underscores the importance of addressing body image concerns as part of comprehensive care for breast cancer patients.