Niger J Clin Pract
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This study aims to investigate color stability and surface roughness of polyetheretherketone (PEEK), zirconia, and hybrid ceramics while stored in different liquids. ⋯ The color change of the materials was within acceptable limits, whereas the surface roughness increased more than 0.2 µm. Especially cola, heptane, and red wine significantly increased the mean surface roughness.
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Regenerative endodontics involves the use of various root canal medicaments and scaffolds, which may cause crown discoloration. ⋯ CH and the modified versions of TAP (mTAPd) and DAP (mDAP) demonstrated an acceptable level of discoloration when used with a combination of PRF at day 90.
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Hearing loss, also termed as hearing impairment, is an ailment where hearing is impaired partially or fully. About one in eight people suffer from hearing loss worldwide. The main aim of this current systematic review was to analyze the clinical effectiveness of cochlear implant (CI) surgery in pediatric and adult patients. ⋯ In the performance of post CI outcomes in patients, the age is not a determinant factor. CI is an effective aid in communication and speech perception for a majority of people with mild to severe hearing loss. Further studies are needed with large databases, patient registries for long term follow up details, higher quality reporting, and longer duration to develop stronger evidence.
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The quality of sexual life of women with type 2 diabetes has an impact on their self-management perceptions. ⋯ There is a relationship between quality of sexual life and self-management perceptions of women with type 2 DM. As the quality of sexual life increases, diabetes self-management perceptions increase. Age affects diabetes self-management perception, and the type of treatment used by individuals also affects their quality of sexual life.
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Docetaxel (DOC) is the main chemotherapeutic agent for the treatment of advanced metastatic prostate cancer. Docetaxel shows anticancer effects by preventing the depolymerization of microtubules in the cell, therefore preventing cell division. However, the low survival effect of docetaxel has prompted researchers to search for novel therapeutic agents. Fucoidan (FUC) is a sulfated polysaccharide derived from brown algae. It has many bioactivities which makes fucoidan a promising anticancer agent. In this study, the potential anti-tumorigenic and preventive effects of fucoidan with or without docetaxel in prostate cancer were investigated by analyzing different cell death modalities. ⋯ According to the findings of this study, FUC inhibited tumor growth temporally and dimensionally, especially in preventive applications. FUC and FUC+DOC combinations in both treatment groups showed anti-tumorigenic effects. The results of this study suggest that fucoidan is a promising anticancer agent against prostate cancer. FUC can be considered as a preventive or treatment agent in prostate cancer therapy with DOC. Further studies are needed to fully elucidate the mechanism of action of fucoidan in metastatic prostate cancer.