Pak J Med Sci
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To determine the correlation between the expression of silent information regulator 1 (SIRT1) and enhancer of zeste two polycomb repressive complex two subunit (EZH2) and peritoneal function in patients with diabetic nephropathy (DN) and peritoneal dialysis. ⋯ Serum SIRT1 and EZH2 expressions in patients with DN undergoing peritoneal dialysis are closely related to their peritoneal function. They have certain diagnostic value for the poor prognosis of patients with DN undergoing peritoneal dialysis.
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To determine the effect of Team-based learning (TBL) on the critical thinking of health professions students. ⋯ TBL improves five out of six dimensions of students' critical thinking. Besides its established evidence to increase knowledge, TBL can also be used as a teaching methodology for enhancing students' critical thinking.
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The incidence of primary hyperparathyroidism (PHPT) is increasing in trend due to more common practice of routine blood investigations especially in the elderly. Surgery is the only curative therapy in symptomatic patients. We present a case of a 63-year-old lady with generalised body weakness associated with occasional muscle cramps. ⋯ Therefore, bilateral neck exploration with intra-operative parathyroid hormone (io-PTH) measurement was performed. The nodular left thyroid and adenomatous right superior parathyroid glands were removed. Possible causes of negative localization and incorporation of io-PTH in under-resourced countries to ensure successful surgery are discussed.
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To investigate the effect of azithromycin on the levels of serum inflammatory factors and T lymphocyte subsets in patients with gynecological mycoplasma infection. ⋯ Azithromycin used in clinical treatment of patients with gynecological mycoplasma infection can effectively improve anti-inflammatory and immune response, improve the clinical efficacy of the treatment and reduce adverse reactions.
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The purpose of our study was to investigate the incidence and prognostic significance of baseline and control uric acid values in COVID-19. ⋯ In our study, hypouricemia was not found to be a major feature of SARS-CoV-2 infection. Low baseline uric acid levels were associated with increased ICU admission. The decline in uric acid levels during hospital stay predicted poor prognosis, as well.