Pak J Med Sci
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To assess the efficacy of muscle energy technique (MET) in combination with conventional physical therapy compared to conventional physical therapy alone following mesenchymal stem cell transplantation in knee osteoarthritis (OA) patients. ⋯ Both groups are effective for improving knee pain, and functional limitation in knee osteoarthritis patients. However, MET Group along with conventional therapy showed marked effects on improving knee pain, knee flexion ROM, and functional limitations after mesenchymal stem cell transplantation in knee osteoarthritis patients.
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Congenital malformations (CM) are structural defects of the human body that arise during development. They significantly impact neonatal outcomes such as morbidity and mortality, hence identification of risk factors and their reduction is vital to improve materno-fetal outcomes. In Karachi, Pakistan, there is insufficient data on the incidence of congenital malformations. Therefore, it is necessary to initiate a prospective case control study. The desired objective was to determine the association of congenital malformations with sociodemographic and maternal risk factors in different ethnicities. ⋯ It was evident that various maternal sociodemographic and risk factors play a significant role in the development of congenital anomalies.
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Healthcare workers are at a higher risk of burnout. The aim of the study was to explore the professional quality of life (QOL) i.e. {Compassion Satisfaction (CS), Burnout (BO) and Secondary Traumatic Stress (STS)} and association of different trainee factors on QOL amongst Pediatric specialty trainees at a private tertiary care hospital in Karachi, Pakistan. ⋯ This study delves into the professional quality of life and offers valuable understanding into the specific events encountered by trainees.
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To investigate the efficacy of sacubitril/valsartan combined with dapagliflozin in diabetic patients suffering from heart failure following an acute myocardial infarction. ⋯ In diabetic patients suffering from heart failure after an AMI, treatment with sacubitril/valsartan combined with dapagliflozin may effectively control blood glucose levels and improve cardiac functions without increasing adverse reactions, indicating high clinical safety.
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Encephalocele is a congenital neural tube defect (NTD). The pathophysiology of the NTDs is exceedingly complex. Numerous explanations have been proposed to explain it. ⋯ Double encephalocele is a rare entity. The multisite closure theory appears to be the most plausible explanation for the development of multiple NTDs. The management of double encephalocele requires a case based approach.