Pak J Med Sci
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To determine the association of serum Vitamin-D levels and placental laminin expression in pre-eclamptic and normotensive women. ⋯ Our results show a strongly positive association between serum Vitamin-D levels, LN expression and severity of histopathological changes between normotensive and pre-eclamptic women.
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Although differentiated thyroid cancers have a good prognosis overall, their incidence is on the rise with extremely limited data available in our region. The objective was to describe the outcomes of differentiated thyroid carcinoma in a tertiary care hospital. ⋯ This study highlights the low cure rate while describing the high rate of disease persistence and recurrence. This can be due to delays related to the diagnosis and scarcity of proper treatment. Recognition of this emergent disease is vital so that curative methods prescribed at proper time can diminish the morbidity and mortality linked with this treatable cancer.
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To assess the efficacy of combined tympanostomy tube insertion (TTI) and adenoidectomy (Ad) versus Ad alone in the treatment of otitis media with effusion (OME) in children. ⋯ Compared to Ad alone, combined TTI+Ad treatment is equally safe and more effective in the treatment of OME in children. This surgical approach is associated with reduced local inflammatory reactions and lower recurrence rate.
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To report on causes and treatment options of hip arthroplasty in younger population in a single center. ⋯ Non-cemented hip arthroplasty was the commonest treatment method in younger population in this study.
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Congenital malformations (CM) are structural defects of the human body that arise during development. They significantly impact neonatal outcomes such as morbidity and mortality, hence identification of risk factors and their reduction is vital to improve materno-fetal outcomes. In Karachi, Pakistan, there is insufficient data on the incidence of congenital malformations. Therefore, it is necessary to initiate a prospective case control study. The desired objective was to determine the association of congenital malformations with sociodemographic and maternal risk factors in different ethnicities. ⋯ It was evident that various maternal sociodemographic and risk factors play a significant role in the development of congenital anomalies.