Pak J Med Sci
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To determine the yield of Gastric lavage (GL) in non-expectorating adults with suspected Pulmonary Tuberculosis (PTB) and accuracy of GL-AFB smear with GL-GeneXpert (GXP) by taking AFB culture as gold standard. ⋯ Yield of GL significant to detect PTB in suspected cases who are not expectorating. GL-GXP diagnostic accuracy and sensitivity is higher than GL-AFB smear.
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Congenital Cataract is a type of ophthalmic genetic disorder that appears at birth or in early childhood. Among 30 genes, CRYBB2 is one of the most common and a water-soluble protein of lens's that code for the βB2-crystallin. This study aimed to investigate the novel silent mutation in CRYBB2 of exon six in the Pakistani families of Autosomal Dominant Congenital Cataracts (ADCC). ⋯ This study investigated a novel important sequence variant in the beta-crystalline protein that causes autosomal dominant congenital cataract (ADCC) in Pakistani families. Thus, our study enlarges the CRYBB2 mutation spectrum and associated phenotypes to help clinical diagnosis of human genetic diseases.
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To find out the role of triglyceride glucose index (TGI) and triglyceride HDL ratio (THR) as predictors of insulin resistance and control of glucose status in type two diabetes mellitus (T2DM). ⋯ TGI and THR have a strong association and predictive capability to identify insulin resistance and detect the development and progression of T2DM. Moreover, TGI can be more precisely used for prediction analysis as compared to THR.
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To assess the congruity of Moyers' dental analysis in Pakistani individuals and to make tables foreseeing the size of non-erupted permanent premolars and canines in children. ⋯ Moyer's prediction cannot be applied to the Pakistani population. Mandibular incisors in addition to maxillary first molars are superior in prediction for the size assessment of canines and premolars (cp) that are unerupted in males and upper arch only in females. Another noteworthy conclusion is that in our study sample, in lower arch of females, the width of mandibular molars with mandibular incisors predicts better.
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To compare the results of local administration of platelet-rich plasma (PRP) with methylprednisolone in the treatment of tennis elbow. ⋯ The study concluded that there is no difference between outcome and efficacy of both treatment modalities used for the treatment of tennis elbow in alleviating pain at 12 months.