Pak J Med Sci
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Determination of hemoglobinopathies is significant for epidemiological studies. There is a need to identify burden of hemoglobinopathies at national level to lay down the foundation of appropriate screening and prevention programs. The present study aimed to evaluate the spectrum of hemoglobinopathies along with hematological and biochemical parameters in a tertiary care hospital. ⋯ Apparently, overall frequency is static however, results of this study are not applicable to general population due to sample bias. Moreover, true figures are difficult to identify due to high incidence of iron deficiency anemia that masks the diagnosis by conventional techniques. Molecular characterization by DNA analysis is the most reliable tool of diagnosis. However, this method is not widely available in our country due to lack of expertise and cost issues.
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The purpose of our study was to investigate the incidence and prognostic significance of baseline and control uric acid values in COVID-19. ⋯ In our study, hypouricemia was not found to be a major feature of SARS-CoV-2 infection. Low baseline uric acid levels were associated with increased ICU admission. The decline in uric acid levels during hospital stay predicted poor prognosis, as well.
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Evidence has shown the innumerable benefits of prenatal physical activity practice; therefore, the knowledge pregnant women have, and efforts to sustain the knowledge and encourage them to engage in prenatal physical activity, are desirable. The objective of the study was to assess the knowledge and attitudes concerning prenatal physical activity of pregnant women attending primary health antenatal care clinics. ⋯ The women had high knowledge of prenatal physical activity, and relatively positive attitudes toward prenatal physical activity. The feeling of tiredness, lack of motivation and inadequate information on physical activity constituted negative attitudes towards physical activity. There is need to provide education and advocacy in the clinical settings; also, interventions to encourage and promote prenatal physical activity in the community and at home are desirable to address the weaknesses identified in this study regarding the women's knowledge and attitudes concerning prenatal physical activity.
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To investigate the effect of azithromycin on the levels of serum inflammatory factors and T lymphocyte subsets in patients with gynecological mycoplasma infection. ⋯ Azithromycin used in clinical treatment of patients with gynecological mycoplasma infection can effectively improve anti-inflammatory and immune response, improve the clinical efficacy of the treatment and reduce adverse reactions.