Presse Med
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PHYSIOLOGICAL AGING: Anatomical and physiological renal changes occur during normal aging in humans. These changes are different from the renal effects of many diseases frequently linked to aging and which require specific diagnosis, prevention and therapy. Renal aging varies from one patient to another or from one population to another. ⋯ However, in old hospitalized patients, acute renal failure is frequent and occurs mainly during inflammatory or infectious disorders, dehydration or drug combinations enhancing regulation of glomerular filtration. Tubular function changes expose the elderly to increasing risk of dehydration which could be prevented in highly predictable situations such as gastrointestinal symptoms, poorly salted diets or anorexia. Estimation of the creatinine clearance is necessary whenever an acute medical events, mostly infectious diseases, occur in elderly people to adapt drugs doses to renal catabolism.
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UTERINE DISORDERS: Because they can prevent implantation, anomalies within the uterine cavity play an important role in fertility. The uterine disorders most often observed during hysteroscopy and implicated in infertility are adhesions, septa, polyps, submucous myomas, adenomyosis, endometritis, anomalies of the cervical canal, and lesions of the uterotubal junction.
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SKIN LESIONS: The concept that patients with subacute cutaneous lupus erythematosus (SCLE) skin lesions represent a distinct lupus erythematosus subset was proposed in 1979 by Sontheimer and supported by many studies. Skin lesions are papulo-squamous, psoriasiform or annular. Photosensitivity is a common complaint and photo-reproduction is significantly frequent in these patients. They persist for weeks or months and typically heal without atrophy or scarring with hyperpigmentation or more often hypopigmentation.