Presse Med
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Letter Case Reports
[Senegal and malaria. True prophylactic failure of mefloquine].
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THE MAIN OBJECTIVES OF THE CRITICAL REVIEW OF THE PUBLICATION OF A CLINICAL TRIAL: Are to underline the biases that may influence the validity and credibility of the results and to assess the quantity of the effect observed and the potential clinical impact.
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Case Reports
[Pulmonary strongyloidiasis complicated by E. coli meningitis in a HIV-1 and HTLV-1 positive patient].
Disseminated strongyloidiasis occurs in immunodepressed patients, notably those infected by retroviruses. ⋯ In HIV-infected patients exhibiting severe strongyloidiasis, research for an HTLV co-infection is recommended.
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THE EFFICACY OF LEVOFLOXACIN: In treating community-acquired pneumonia (CAP) has been assessed during 5 large clinical trials (including 4 controlled randomized trials). 1067 PATIENTS HAVE BEEN TREATED BY LEVOFLOXACIN: And 645 by a comparator. Success rates were identical between levofloxacin and comparator ranging from 70.6% to 84.2% for levofloxacin treated patients, and from 75% to 85.7% for comparators treated patients. 549 PRESUMED OR PROVED PNEUMOCOCCAL PNEUMONIA: Have been treated by levofloxacin with a success rate ranging from 83% to 100%, and 379 have been treated by a comparator with a success rate ranging from 90% to 95%. ⋯ The severity of the patients ranged between studies from moderate to severe. PROOFS COMING FROM THOSE CLINICAL TRIALS: Show the efficiency of levofloxacin in the treatment of moderate to severe community acquired pneumonia in adults, and in the treatment of presumed or proved pneumonia, with or without bacteraemia.
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CRANIO-ENCEPHALIC TRAUMAS: Scanography remains the examination of choice. However, MRI can be useful in diagnosis of diffuse axional lesions, not clearly visualized with scanography, and for screening the subsequent lesions. ⋯ If multiple sclerosis is suspected, MRI is considered as the principle para-clinical examination able to confirm the diagnosis with the first episode. It also supplies data for the diagnosis of metabolic, toxic and degenerative diseases.