Rev Assoc Med Bras
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Randomized Controlled Trial
[Synergistic effect between dexmedetomidine and 0.75% ropivacaine in epidural anesthesia].
This study aimed to evaluate clinical characteristics of epidural anesthesia performed with 0.75% ropivacaine associated with dexmedetomidine. ⋯ There is clear synergism between epidural dexmedetomidine and ropivacaine, further this drug association does not bring about additional morbidity.
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This prospective non-interventional study intended to assess the prognostic value of gastric intramucosal acidosis in patients with severe trauma admitted to a medical/surgical ICU. ⋯ Bicarbonate, base deficit, lactate, gastric intramucosal pH and PCO2 gradient discriminate survivors from nonsurvivors of major trauma. A critical air PCO2 gradient carried the greatest relative risk for death at 24 hours of ICU. Inadequate regional blood flow as detected by a critical PCO2 gradient seems to contribute to morbidity and mortality of severe trauma patients.