Rev Assoc Med Bras
-
Randomized Controlled Trial
Norepinephrine infusion increases urine output in children under sedative and analgesic infusion.
To evaluate the effects of early norepinephrine (NE) infusion in children submitted to mechanical ventilation (MV) requiring continuous sedative and analgesic infusion. ⋯ Early norepinephrine infusion in children submitted to MV improves mean arterial pressure and increases urine output. These effects were attributed to reversion of vasoplegia induced by the sedative and analgesic drugs.