Rev Invest Clin
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In this study are evaluated the usefulness of the buffy coat smear and panbacterial polymerase chain reaction (PCR) as diagnostic tests in the early detection of neonatal sepsis. ⋯ Buffy coat smear stains are easy, fast, and specific, while that of PCR was highly sensitive. Thus, both can be utilized as diagnostic tests.
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Comparative Study
[Associated factors to extubation failure of neonates and infants with bronchopulmonary dysplasia].
The extubation failure is a common problem in newborn (NB) and infants diagnosed with bronchopulmonary dysplasia (BPD), a situation that prolongs the mechanical ventilatory support (MVS) and increases the risk of further laryngotracheal and pulmonary damage that predisposes to fail in the procedure. There are no studies in the literature about this problem. ⋯ The study population consisted of 89 patients who were divided into 2 groups: group A (cases) with 69 patients and group B (controls) with 20 patients. The characteristic of the population studied in both groups showed no significant differences between them with p > 0.05. In multivariate analysis before the first extubation showed statistically significant patent ductus arteriosus for cases with p = 0.01. Before the second extubation in the cases group versus before the first extubation in the control group showed also in the multivariate analysis statistical significance only peak inspiratory pressure (PIP) > or = 14 cm H2O (in 3 of 69 cases and in 16 of 20 controls) (p < 0.001), as a protective factor. CONCLUSIONS. Patients with BPD the extubation should be planned closure of the ductus arteriosus when present, even without hemodynamically significant and with ventilator parameters most demanding as PIP would be > or = 14 cm H2O and moreover the latter in the second attempt at extubation, and to take into account other aspects known to decrease the incidence of extubation failure as far as possible, with improved prognosis.