Saudi Med J
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To identify biomarkers that can discriminated small cell lung cancer (SCLC) from non-SCLC (NSCLC), and explore their association with the prognosis of SCLC under chemoradiotherapy. ⋯ MTHFD1 expressions might be a novel specifically prognostic biomarker for SCLC and the CRT treatment outcome.
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Observational Study
Effect of the prone position on mechanical power in elective surgical patients under general anesthesia: A prospective observational study.
To evaluate how the prone position influences mechanical power (MP) during elective surgical procedures. ⋯ Position changes influence MP. Returning to the prone position increases MP. An increase in BMI is associated with an increase in MP.ANZCTR Reg. No.: ACTRN12623001281684.
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To investigate whether magnetic resonance imaging (MRI) best detects early malignancy in high-risk women. ⋯ Magnetic resonance imaging is more effective than US and mammography for early detection of BC. It showed high sensitivity in detecting breast lesions and high specificity in characterizing their nature when correlated with pathological results. Ultrasound screening followed by MRI is suggested for undetected or suspected lesions. This will increase the breast lesion detection rate, reduce unneeded tissue biopsies, and enhance the disease's survival rate.
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To evaluate the potency of Manuka honey UMF +15 against Carbapenem-resistant Enterobacterales (CRE). Bacterial resistance is a worldwide problem that is increasing year by year, especially Carbapenem resistance. Alternatives to antibiotics are needed to both reduce costs, and to reduce the spread of antibiotic resistance, with the ultimate goal of saving lives. ⋯ This study shows the remarkable antibacterial activity of Manuka honey and suggests that this natural remedy might be used in the future as an alternative treatment option against Carbapenem-resistant Enterobacterales (CRE); however, further clinical trials should be performed to corroborate our initial findings.
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To investigate the correlation between psychological resilience and well-being, considering various demographic factors within a Saudi society. ⋯ Psychological resilience and well-being are essential variables that warrant consideration in future mental health research.