Saudi Med J
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To provide insights into the real-world usage of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2i) among individuals with type 2 diabetes (T2D) from Bahrain, Kuwait, and Qatar who either had established atherosclerotic cardiovascular disease (eASCVD) or were at high risk of developing ASCVD. ⋯ Despite these cardioprotective agents being recommended by guidelines, the study findings suggest a suboptimal use of GLP-1RA and SGLT2i in a real-world setting.
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To evaluate whether hypothyroidism is a risk factor for transient ischemic attack (TIA). ⋯ Hypothyroidism, particularly clinical hypothyroidism, may be an independent risk factor for TIA.PROSPERO No. ID: CRD42024552608.
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To review the outcomes of the cochlear implantation program at King Abdallah Medical Center (KAMC) in Makkah from its launch in 2018 to 2023, focusing on patient demographics, procedural details, and complications. ⋯ The CI program at KAMC has demonstrated to be a safe and effective approach for treating severe-to-profound hearing loss. Minor complications were observed, and follow-up adherence was strong. The study emphasizes the importance of ongoing accreditation and support for the program to ensure its success in hearing rehabilitation.
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To investigate epidemiological changes in respiratory fungal infections (RFI), including fungal isolation and colonization, at one of the main centers in Medina. The incidence of RFI is rising due to an increase in the number of immunocompromised individuals, a higher prevalence of respiratory viral infections, and an aging population. ⋯ Candida albicans was the leading cause of RFI. Continuous monitoring, improved diagnostics, and targeted interventions are crucial to address existing challenges and emerging threats. The growing recognition of fungal infections necessitates increased research and education for healthcare professionals.
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Observational Study
Concordance between homeostatic model assessment and triglyceride glucose index in assessing insulin resistance among HIV-infected patients.
To evaluate the concordance between the triglyceride glucose (TyG) index and the homeostatic model assessment of insulin resistance (HOMA-IR) in assessing insulin resistance (IR) in people living with HIV (PLWH). Additionally, we aimed to estimate a cut-off value for the TyG index in PLWH. ⋯ Our study identified correlation between the TyG index and HOMA IR index in PLWH. The TyG index may serve as an effective alternative to HOMA-IR for evaluating insulin resistance in PLWH.".