Singap Med J
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Case Reports
CT and MR findings in central pontine and extrapontine myelinolysis--a study of two patients.
Central pontine and extrapontine myelinolysis is a distinctive clinical syndrome and has characteristic CT and MR features. We describe two patients who presented with nasopharyngeal carcinoma, severe hyponatremia, and had quick correction of hyponatremia. ⋯ Neurologic recovery was good in one case, and initially seen in the other patient before death resulted from septicaemia. Peripheral enhancement of the basal ganglia and caudate nuclei was seen in one patient, which we believe is a new feature.
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The aim of this study was to find the dosage and pattern of neuroleptic drug utilisation for the treatment of acute schizophrenia in a general psychiatry ward. This is an uncontrolled study involving 112 schizophrenic inpatients. Patients' socio-demographic variables, the type and peak daily doses of neuroleptics prescribed to them were analysed. ⋯ Low potency drugs were prescribed in lower doses than high potency drugs. Patients treated with depot preparation tended to receive higher doses of medication than those prescribed oral medication alone. The doses of neuroleptics were significantly correlated with duration of admission.
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A 78-point self-administered questionnaire relating to headaches was completed by 1208 undergraduates of the National University of Singapore. The management and characteristics of the study population that had sought medical consultation for their headaches was studied. The lifetime prevalence of headaches in the study population was 98.1%. ⋯ No significant gender predisposition was found. Eight of the 106 (7.5%) had been given prophylactic/interval therapy. A significant proportion of the study population responds well to non-prescription medication, suggesting that the purpose of many medical consultations may be to relieve anxieties regarding the diagnosis rather than to obtain symptomatic relief.