Singap Med J
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Randomized Controlled Trial Clinical Trial
The addition of intrathecal sufentanil and fentanyl to bupivacaine for caesarean section.
Intrathecal sufentanil has recently been used in labour as part of a combined spinal epidural technique. This study was conducted to compare its use in combination with bupivacaine for caesarean section with fentanyl added to bupivacaine and bupivacaine alone. ⋯ The addition of 10 micrograms of sufentanil and 15 micrograms of fentanyl to 7.5 mg of bupivacaine prolonged the duration of effective analgesia and improved intra-operative analgesia. However, the incidence of pruritus and episodes of desaturation were increased more with 10 micrograms sufentanil than with 15 micrograms fentanyl.
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Review Case Reports
Severe laryngospasm without intravenous access--a case report and literature review of the non-intravenous routes of administration of suxamethonium.
Severe laryngospasm may occur during inhalational induction of paediatric patients. Effective and rapid treatment of this complication is extremely important to prevent severe hypoxia. The treatment of choice is intravenous suxamethonium if muscle relaxation is desired. ⋯ The rapidity and the effectiveness in treating laryngospasm by these non-intravenous routes are important to the outcome of the patient. Though the intramuscular route may be relatively slower in onset time (time taken to reach maximum effect of paralysis) compared with the intravenous route, clinical experience so far indicates satisfactory result in the treatment of laryngospasm. Current evidences indicate that the intraosseous route is probably superior to the intramuscular route and comparable to the intravenous route in terms of onset time.