Terapevt Arkh
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In 1850 patients with intravenous catheters, intravenous shunts and fistulas sepsis developed in 0.43%. Infection of the catheters and shunts was more frequent than sepsis development. The growth of microorganisms (Staphylococcus aureus, Gram-negative microbes) was noted during a bacteriological study of 300 removed catheters in 27.7%. ⋯ Its early diagnostic signs were described. Immunological changes in the patients with angiogenic sepsis were evaluated. The problems of pathogenesis and prevention of angiogenic sepsis were given due attention.
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The paper is concerned with an analysis of combined use of modern methods of diagnostic imaging for spot biopsy and therapeutic manipulations in 274 patients with various chest diseases. Morphological diagnosis was verified in 252 of 274 examined patients (91.9%). X-ray or CT-assisted therapeutic manipulations with sanitation and drainage of pathological cavities were performed in 12 patients with pulmonary and mediastinal abscesses.
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Comparative Study
[Clinico-morphological features and the course of glomerulonephritis in hemorrhagic vasculitis].
Peculiarities of a clinical course and prognosis of glomerulonephritis in Schönlein-Henoch disease (SH-nephritis) were studied in 42 adult patients. The 5- and 10-year survival rates were 87% and 72%, respectively. ⋯ SH-nephritis was characterized by a more severe course in male patients, in persons aged over 30, and in the involvement of the kidneys one year and more after the appearance of the first clinical signs of skin vasculitis. The level of blood serum IgA and the gravity of skin vasculitis had no prognostic importance.
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The paper is concerned with an analysis of the results of the method of cryoheparinoprecipitation of plasma proteins in patients with immune complex pathology. The essence of the method is that in plasma cooling cryofibrinogens, cryoglobulins, immune complexes and other components of the complement system aggregate and precipitate. The process is potentiated by adding heparin to the plasma. ⋯ Signs of the abdominal, dermal and articular syndrome were eliminated in all the patients; the urinary syndrome was retained in half of the cases necessitating other therapeutic modalities. A CIC level investigated by a method of precipitation with 3.5% polyethylene glycol was not a criterion of assessment of the gravity of diseases: in cases of its increase before therapy initiation there was a clear tendency to a decrease and normalization by the end of treatment. In hemostasis investigation hypercoagulation activation and hyperfibrinogenemia were revealed in most of the patients.(ABSTRACT TRUNCATED AT 250 WORDS)
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A method of apheresis of plasma euglobulin fraction, cryoglobulins and Willebrand factor was developed. In one session of plasmapheresis 1500-1700 ml of patient's plasma were removed, fractionated and returned. The method was used in 2 patients with immune complex vasculitides. ⋯ A decrease in the content of plasma cryoglobulins, cryofibrinogen, and urine protein concentration (from 1.5 up to 0.03%) was noted in the other case. A possibility of the use of the method in other pathological conditions (DIC-syndrome, unstable angina, atherosclerotic angiopathy) accompanied by endothelial damage, was discussed. Willebrand factor multimers form complexes with low density lipoproteins therefore the removal of these complexes may be useful in the treatment of hypercholesteremia and atherosclerosis.