Terapevt Arkh
-
Randomized Controlled Trial Comparative Study Clinical Trial
[The outpatient treatment possibilities for patients with exacerbated peptic ulcer].
The efficacy of hospital and ambulatory treatment of patients with peptic ulcer exacerbation was compared. 209 patients were treated in the hospital and 116 on an ambulatory basis. No appreciable differences were found in the times of the removal of the painful syndrome or gastroduodenal ulcer healing. At the same time early relapses were recorded in 26.4% of the inpatients and in 14.9% of the outpatients. Indications for the treatment of outpatients with gastroduodenal ulcers were developed: rare relapses, lack of complications, moderate painful syndrome, small ulcer dimensions, a possibility of arranging good treatment and control over ulcer healing, favourable living conditions, and being in a positive mood for outpatient treatment.
-
Comparative Study
[Immunosuppressive therapy with the use of cyclosporin A in the late period after a kidney transplant].
A study was made of the results of kidney transplantation in 90 patients who received three-component immunosuppressive therapy (cyclosporin, azathioprine and prednisolone) in the induction phase, followed by cyclosporin conversion in the phase of maintenance therapy. The second patients' group (39 cases) received permanent three-component immunosuppressive therapy. Analysis of the data obtained makes it possible to regard the use of cyclosporin advisable not only in the induction, but also in the maintenance phases of immunosuppressive therapy.
-
Gallbladder function and lipid composition of bile were examined for the first time in the indigenous population of the extreme north of the USSR. Bile from Evens and Evenki was not found to be oversaturated with cholesterol, with motor function of the gallbladder being characterized by hypermotility. This is of interest, since there are data on the protein-lipid nature of nutrition in aborigines of the North.
-
Comparative Study
[The neuroendocrine reactions in patients with chronic bronchitis in a region of the northeastern USSR].
The author describes differences in the manifestations of mutually determined reactions of the sympathoadrenal and hypophyseoadrenocortical systems in their interaction with the biologically active substance serotonin in healthy persons (124) and patients suffering from chronic bronchitis at different times of living on the Chukot Peninsula. The most perfect system of the protective effect on the part of the neuroendocrine complex can be seen in chronic bronchitis patients within the first 3-5 years of living in the North as compared with the reaction of the neuroendocrine system in the examined patients with a longer "northern record" (10-15 years and more).