Terapevt Arkh
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Comparative Study
[The mechanisms regulating pulse-wave spreading time in a biological feedback regimen in patients with borderline arterial hypertension and in healthy subjects].
The regulatory mechanisms of pulse transit time (PTT) during biofeedback training were studied by noninvasive cardiovascular monitoring in borderline hypertensive and normotensive subjects. Hemodynamic parameters were used as indirect indices of autonomous nervous system activity. All the patients were capable of increasing PTT. ⋯ In the initial 5 sessions, there was the most significant decrement of sympathetic, especially beta-adrenergic activity, expressed in the reduction of the myocardial contractility and cardiac output. In the retraining period (6 to 12 sessions), the leading role was played by the reduction of the arterial tone and total peripheral resistance. Respiratory arrhythmia rose in both cases as a result of the increased parasympathetic activity.
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Organization of the management of outpatients with a transplanted kidney is described. The basis of such organization is formed by documentation of the patients' status during the entire observation period in a special card containing the data on the donor; distant monitoring of cyclosporin A for patients living far from the clinic; training of patients. ⋯ They are pyelonephritis of the transplant, essential hypertension and symptomatic hypererythrocytosis. The 2-year survival of the patients is 70.8%, that of the transplant 73.1%.
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Local antirheumatic therapy is viewed as an important component in the total system of the treatment of rheumatic diseases. Drug-induced synovectomy, local anti-inflammatory, antifibrotic and potential immunosuppressive therapy are analyzed. ⋯ There is possibility to improve the results of general therapy at the expense of goal-oriented local treatment without producing any influence on its tolerance. In fact, every patient with rheumatoid arthritis or other articular disease should be regarded as a potential candidate for local anti-inflammatory therapy.
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Comparative Study
[A method for the early detection and treatment of patients with iron deficiency states].
In order to optimize the identification of persons with iron deficiency during mass prophylactic screenings, a diagnostic algorithm using a unified questionnaire was proposed and introduced into medical practice. During 1985-1987, a total of 3655 women aged 18 to 54 years belonging to different occupational groups filled in questionnaires at an industrial enterprise of Novosibirsk. The women were distributed into several groups: group I was made up of normal persons, group II of persons at risk, group III of persons with latent iron deficiency, group IV of persons with iron deficiency anemia, and group V of patients with continuously relapsing iron deficiency anemia refractory to therapy. Taking into account the groups indicated, the diagnostic and the treatment and prophylactic measures have been elaborated.