Terapevt Arkh
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Randomized Controlled Trial Comparative Study Clinical Trial
[The efficacy of bifidum-containing preparations in enterogenous reactive arthritis].
Analysis is made of the intestinal microflora in 43 patients suffering from reactive arthritides (ReA) that developed after intestinal infection. The overwhelming majority of the patients manifested a decrease of the level of the bifidoflora. ⋯ Bifidumbacterine was found to produce a significant beneficial effect on the course of ReA and to cause no serious side effects. According to the preliminary data, the efficacy of bifidumbacterin exceeded that of the known basic drug salazopyridazine, thus making it possible to apply the bifidum-containing drugs as basic agents in the treatment of ReA.
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Case Reports Comparative Study
[The importance of Holter ECG monitoring in the diagnosis of latent arrhythmias in patients with acute respiratory viral infections].
Altogether 37 patients suffering from influenza and acute respiratory viral infections were examined. In 25 patients, acute infections ran their course in association with coronary heart disease. According to the ECG readings, 15% of the patients had rhythm and conduction disorders. Meanwhile Holter ECG monitoring revealed the above disorders in 70% of the patients afflicted with influenza and acute respiratory viral infections.
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Comparative Study
[The lipid metabolic characteristics of patients with thyroid pathology living in the European north of the USSR].
The blood content of total lipids, triglycerides, total cholesterol, alpha- and beta-lipoprotein cholesterol was measured in 79 patients with diffuse toxic goiter during treatment, in 25 patients with hypothyroidism, in 33 with thyroid hyperplasia, and in 54 healthy women aged 35-60 years from the group of native population of the European North. In all the forms of thyroid dysfunction, the patients manifested dyslipoproteinemia in the form of hypercholesterolemia with an increase of the concentration of beta-cholesterol, hypertriglyceridemia, and with a rise of the cholesterol atherogenic index to 4.0 and over. The signs of dyslipoproteinemia were marked to the greatest degree in thyrotoxicosis, at the stages of euthyroidism attainment or disease remissions.
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Comparative Study Clinical Trial Controlled Clinical Trial
[The therapeutic potentials of magnesium sulfate in bronchial asthma].
Twelve patients with preasthma (PA) and 27 bronchial asthma (BA) patients were examined for the effect of magnesium sulphate aerosol on bronchial sensitivity and reactivity to acetylcholine (ACC) and graded physical exercise (GPE) as well as on bronchial patency recorded by general plethysmography and pneumotachography. Inhalation of the drug was established to exert no bronchodilatory action but reduced, as compared with placebo, nonspecific hyperreactivity of the bronchial tree and blocked the ACC induced increment of histamine in the exhaled air condensate. The data obtained allow bronchial smooth muscles and mast cells to be regarded as targets for magnesium sulphate. The drug properties discovered may serve a prerequisite for its use in the combined treatment of BA patients and those with PA.