Turk J Med Sci
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The aim of this study is to determine the risk of cancer in patients with primary Sjögren syndrome (pSS) from a single center in Turkey. ⋯ The risk of hematological and solid cancers was higher in the patients with pSS when compared to general population. In our pSS cohort, the risk for ovarian cancer was found to be increased, which has not been previously reported in the literature.
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This study aimed to investigate the effectiveness of a supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with antitumor necrosis factor (TNF) therapy in anti-TNF-naive patients with active ankylosing spondylitis (AS). ⋯ The supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with anti-TNF therapy is more effective than only anti-TNF therapy in anti-TNF-naive patients with active AS.
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Alzheimer's disease (AD) is a major cognitive disorder classified as a common type of dementia. Magnetic resonance imaging (MRI) is the most practical method for diagnostic purposes in AD. The aim of the study was to determine the volume of the hippocampus and intracranial structures in AD using MRI. ⋯ The most efficient volumetric study in AD could be performed by obtaining long-term periodic morphometric data of an early diagnosed and regularly followed-up patient population.
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In tuberculsosis (TB), miRNA has been used as a biomarker to distinguish between healthy individuals and TB patients. The aim of this study was to investigate (i) the association of the miRNA and cytokine expression levels, the course of tuberculosis infection, clinical forms and response to treatment, and (ii) the effects of genotypic features of bacteria on the course of tuberculosis and the relationship between miRNA and cytokine expressions and bacterial genotypes. ⋯ There is no significant relationship between the clinical course of the disease, cytokine and miRNA expression, and the genotype of the bacteria.
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Outcomes of transcorneal electrical stimulation therapy in the early stages of retinitis pigmentosa.
To investigate the effect of transcorneal electrical stimulation (TES) therapy in patients with retinitis pigmentosa (RP). ⋯ The TES therapy may be an effective and safe treatment modality in slowing the RP progression, especially in the early stages of the disease. Longer-term follow-ups in larger patient populations are warranted.