Vojnosanit Pregl
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Comparative Study Clinical Trial
[Analgesic efficacy of Famalgin and Imigran in patients with acute migraine attacks].
Migraine is a syndrome clinically manifested in attacks which dominant symptom is unilateral, rarely generalized, recurrent headache that can last for hours, and occasionally, days. According to different sources, it is considered that about 10-15% of world population suffers from some type of this syndrome. ⋯ Trial results revealed significant analgesic efficacy of both preparations without significant differences in analgesic effect, with significantly better tolerability of Famalgin. It was concluded that both preparations were efficacious drugs for the treatment of headache as the most prominent clinical symptom of migraine, with significantly rarer and less pronounced adverse effects of Famalgin.
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In the period from January 1985 till January 1995 in the Clinic of Traumatology and Orthopedics of Military Medical Academy were treated 305 patients with 317 primary amputations of the lower extremities that were performed as the sequelae of ischemia and necrosis on the basis of occlusive changes, arteriosclerosis and diabetes. Out of the total number of operated patients, 210 were with diabetes mellitus. ⋯ Reamputations were performed in 52 patients (16.4%): at the level of foot in 22 (6.94%), lower leg in 17 (5.36%) and upper leg in 13 patients (4.10%). Tourniquet was used during the surgery of primary amputation in 56 patients.