W Indian Med J
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To systematically assess the efficacy and safety of montelukast for postinfectious cough (PIC) and to propose a recommendation via a systematic review of all available randomized controlled trials (RCTs). ⋯ Montelukast demonstrated potential positive efficacy and safety for PIC; however, we could not come to a firm conclusion on the efficacy and safety of montelukast for PIC. More high quality randomized controlled trials are required to confirm the efficacy and safety of montelukast for PIC.
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The objective of this study was to develop a sonographic technique for the measurement of fetal interorbital distance (IOD) for gestational age (GA) determination and to establish a normogram of IOD for the local population. ⋯ Results from the study suggest that the fronto-transverse technique is a feasible and reproducible technique for IOD measurement and the established normogram of IOD can be a veritable statistic for GA prediction in our locality.
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Accurate prediction of ovulation is important in the management of female infertility. ⋯ Sonographic observation of complete disappearance of a dominant follicle and reduction in follicular size of surrogate follicles after follicular rupture appeared to be a reliable predictor of imminent ovulation.
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Health-related quality of life (HRQOL) measurement is used for assessing the impact of diseases and medical treatments on physical, psychological and social aspects of an individual's health and life. The Paediatric Quality of Life Inventory™ (PedsQL™) is a widely used instrument to measure paediatric HRQOL in children. The aim of this study is to investigate the HRQOL in paediatric patients with acute lymphoblastic leukaemia and determine the precautions for improving the quality of their life. ⋯ It is thought that determination of the psychosocial, as well as the physical impacts of the disease on the child, will positively influence the treatment given by improving the quality of life of both the child and the family.
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To examine the role of variations in vascular endothelial growth factor (VEGF) and pigment epithelial-derived factor (PEDF) levels and VEGF/PEDF ratio in predicting the occurrence of retinopathy of prematurity (ROP) in extremely premature human babies. ⋯ Increased expression of VEGF levels was found to be associated with older postnatal day age in our study. Monitoring of variations in VEGF level and PEDF/VEGF ratio might be helpful in predicting the occurrence of ROP in premature human babies.