Neurology
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Review Multicenter Study Meta Analysis Comparative Study
Direct oral anticoagulant- vs vitamin K antagonist-related nontraumatic intracerebral hemorrhage.
To compare the neuroimaging profile and clinical outcomes among patients with intracerebral hemorrhage (ICH) related to use of vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) for nonvalvular atrial fibrillation (NVAF). ⋯ DOAC-related ICH is associated with smaller baseline hematoma volume and lesser neurologic deficit at hospital admission compared to VKA-related ICH.
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To report the clinical features of myasthenia gravis (MG) induced by treatment with immune checkpoint inhibitors using 2-year safety databases based on postmarketing surveys in Japan. ⋯ The prompt and correct recognition of MG following treatment with immune checkpoint inhibitors in patients with cancer is important.
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Multicenter Study Observational Study
Prognostic relevance of MOG antibodies in children with an acquired demyelinating syndrome.
To assess the prognostic value of MOG antibodies (abs) in the differential diagnosis of acquired demyelinating syndromes (ADS). ⋯ Our results show that the presence of MOG-abs strongly depends on the age at disease onset and that high MOG-ab titers were associated with a recurrent non-MS disease course.
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Observational Study
Magnesium, hemostasis, and outcomes in patients with intracerebral hemorrhage.
We tested the hypothesis that admission serum magnesium levels are associated with hematoma volume, hematoma growth, and functional outcomes in patients with intracerebral hemorrhage (ICH). ⋯ These data support the hypothesis that magnesium exerts a clinically meaningful influence on hemostasis in patients with ICH.