Scandinavian journal of gastroenterology
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Scand. J. Gastroenterol. · Mar 1998
Randomized Controlled Trial Clinical Trial13C-urea breath test for the diagnosis of Helicobacter pylori infection. A further simplification for clinical practice.
The 13C-urea breath test is the most accurate noninvasive method for the diagnosis of Helicobacter pylori infection. The oral administration of citric acid solution as test drink 10 min before administration of 13C-urea appears to be the most valuable test procedure hitherto reported. To simplify the test for clinical routine, we evaluated in a prospective, randomized, crossover study the accuracy of a new modification that consists in giving the 13C-urea dissolved in the test drink. ⋯ The 13C-urea breath test for the diagnosis of H. pylori infection can be simplified by giving the substrate dissolved in the test drink. This modification is not associated with a loss of diagnostic accuracy.