Scandinavian journal of gastroenterology
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Scand. J. Gastroenterol. · Aug 2006
Inhibitory effects of gastric electrical stimulation on ghrelin-induced excitatory effects on gastric motility and food intake in dogs.
To investigate the effects of ghrelin on food intake, gastric motility and whether gastric electrical stimulation (GES) is capable of reversing these effects of ghrelin in dogs. ⋯ Ghrelin induces antral contractions and increases food intake. GES is capable of blocking these excitatory effects of ghrelin. These findings suggest that GES may inhibit the resistant effect of ghrelin on weight loss.