Scandinavian journal of gastroenterology
-
Scand. J. Gastroenterol. · Dec 2013
Comparative StudyComparison of registered and published primary outcomes in randomized controlled trials of gastroenterology and hepatology.
OBJECTIVES. The need for trial registration as well as the benefits it has brought for the transparency of medical research has been recognized for years. Trial registration has turned from an exception to a mandatory guideline in recent years. ⋯ CONCLUSIONS. Based on the results of the present study, selective outcome reporting of gastroenterology RCTs published in leading medical journals has been much improved over the past years. However, there might be a sampling bias to say that consistency of registered and published POs of gastroenterology RCTs has been better than before.